CLONING AND CHARACTERIZATION OF THE MOUSE MCOLN1 GENE REVEALS AN ALTERNATIVELY SPLICED TRANSCRIPT NOT SEEN IN HUMANS

Cloning and characterization of the mouse Mcoln1 gene reveals an alternatively spliced transcript not seen in humans

Abstract Background Mucolipidosis type IV (MLIV) is an autosomal recessive lysosomal storage disorder characterized by severe neurologic and ophthalmologic abnormalities.Recently the MLIV gene, MCOLN1, has been identified as a new member of the transient receptor potential (TRP) cation channel superfamily.Here we report the cloning and characteriza

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Mixed convection from a discrete heat source in enclosures with two adjacent moving walls and filled with micropolar nanofluids

This paper examines numerically the thermal and flow field characteristics of the laminar steady mixed convection flow in a square lid-driven enclosure filled with water-based micropolar nanofluids by using the finite volume method.While a uniform heat source is located on a part of the bottom of the enclosure, both the right and left sidewalls are

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Ranging of older male elephants introduced to an existing small population without older males: Pilanesberg National Park

The African elephant Loxodonta africana is one of the key components of African savanna.Not only do they play a crucial role in the ecosystem (Dublin et al.1990; Van de Vijver et al.1999), but they also provide one of the integral parts of sustainable conservation through ecotourism (e.g.Brown Custom Hoodie 1993) and consumptive utilisation (Taylor

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